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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Mol Ther. 2008 Aug 26;16(11):1783–1788. doi: 10.1038/mt.2008.185

Figure 2.

Figure 2

Figure 2

Kaplan-Meier survival curves of athymic nude mice after intracranial implantation of human U87-MG cells and treatment by stereotactic CED of d106, d109, or HBSS and irradiation (0 and 10 Gy). Animals surviving 80 days post-tumor implantation were sacrificed. a, Kaplan-Meier survival curve comparison of athymic nude mice which underwent intracranial implantation of U87-MG cells and treatment by stereotactic CED of d106 or HBSS and irradiation (0 and 10 Gy). Control animals were mice that underwent CED of HBSS and did not receive ionizing radiation (IR). Statistical significance, P < 0.001 by log-rank method of CED of d106 and irradiation compared to CED HBSS and irradiation (n=10 per group). b, Kaplan-Meier survival curve comparison of athymic nude mice which underwent intracranial implantation of U87-MG cells and treatment by stereotactic CED of d106 or d109 and irradiation (0 and 10 Gy). Control animals were mice that underwent CED of d109 and did not receive IR. Statistical significance, P < 0.001 by log-rank method of CED of d106 and irradiation compared to d109 CED and irradiation (n=10 per group).