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. Author manuscript; available in PMC: 2009 Oct 31.
Published in final edited form as: Cell. 2008 Oct 31;135(3):561–571. doi: 10.1016/j.cell.2008.08.040

Fig. 1. Distribution of mouse GPCR mRNA expression in vivo.

Fig. 1

A) The number of GPCRs expressed in tissues presented in pie chart form. Receptors expressed in all 41 tissues assayed are “ubiquitous”; receptors expressed in more than or less than half are “widespread” or “restricted”, respectively. A list of the “ubiquitous” receptors is included in Table 1. B) GPCR expression by tissue systems. High, medium, low and absent are defined in Results. Tissue systems are defined as: Central Nervous System (CNS: cerebellum, brainstem, hypothalamus, cerebral cortex, hippocampus, striatum, olfactory bulb, olfactory epithelium, retina, whole eye), Endocrine (pituitary gland, islets of Langerhans, adrenal gland, thyroid/parathyroid), Cardiovascular (aorta, vena cava, heart atrium, heart ventricle), Pulmonary (lung, trachea), Metabolic (brown adipose tissue, white adipose tissue, isolated adipocytes, liver, skeletal muscle, kidney), Gastroenteric (pancreas, gall bladder, large intestine, small intestine, stomach, urinary bladder), Reproductive (ovary, testes, uterus), Barrier (tongue, esophagus, skin) and Immune (spleen, thymus, bone marrow). A list of the highly expressed GPCRs in individual tissue systems is included in Table 1.