Table 2.
Measures Used
| Pre-Pubertal | Post-Pubertal | ||||||
|---|---|---|---|---|---|---|---|
| PND 34 | PND 37-39 | PND 40-42 | PND 56 | PND 59-61 | PND 62-64 | PND 80 | |
| Group 1 | apomorphine- stereotypy1 |
novel-2, and amphetamine1- locomotion |
haloperidol1 -catalepsy |
apomorphine1- stereotypy |
novel2-, saline2- , and amphetamine1- locomotion |
haloperidol1- catalepsy |
3H- Haloperidol4, 3H-MK-8015, 3H-GBR- 129356 binding |
| Group 2 | apomorphine- stereotypy1 |
novel2- and amphetamine1- locomotion |
novel2, and MK-8013- locomotion |
apomorphine1- stereotypy |
novel2- and amphetamine1- locomotion |
novel2 and MK- 8013- locomotion |
|
1
dopamine-mediated behaviors
2
behavioral alterations to stress
3
behaviors mediated by the NMDA
4
dopamine binding
5
binding to the NMDA glutamate receptor
6
binding to the dopamine transporter