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. Author manuscript; available in PMC: 2009 Aug 10.
Published in final edited form as: J Comp Neurol. 2008 Aug 10;509(5):474–492. doi: 10.1002/cne.21770

Figure 7.

Figure 7

Overexpression of BMP4 under the control of the NSE promoter increases the proportion of enteric neurons that express TH and TrkC. A. The overall density of neurons in the submucosal plexus in WT and BMP4-overexpressing mice is not significantly different. B. The overall density of neurons in the myenteric plexus in WT and BMP4-overexpressing mice is not significantly different. C. The proportion of submucosal neurons that expresses TH is significantly (* p < 0.03) greater in BMP4-overexpressing (n = 36) than WT mice (n = 32). D. TH immunoreactivity in the submucosal plexus of a WT mouse. E. TH immunoreactivity in the submucosal plexus of a BMP4-overexpressing mouse. F. TrkC immunoreactivity in the submucosal plexus of a WT mouse. G. TrkC immunoreactivity in the submucosal plexus of a BMP4-overexpressing mouse. H. The proportion of submucosal neurons that expresses TrkC is significantly (* p < 0.05) greater in BMP4-overexpressing than in WT mice. I. TrkC immunoreactivity in the myenteric plexus of a WT mouse. J. TrkC immunoreactivity in the myenteric plexus of a BMP4-overexpressing mouse. K. The proportion of myenteric neurons that expresses TrkC is significantly (** p < 0.01) greater in BMP4-overexpressing than in WT mice. The bars = 60 μm.