Table 1.

Two-point LOD score obtained between the disease in family BUIT-CA01 and each marker locus

	LOD score values at θ
Marker	0.0	0.1	0.2	0.3	0.4
D16S397	5.4	4.3	3.2	2.0	0.8
D16S3086	5.4	4.3	3.2	2.0	0.8
D16S421	5.6	4.5	3.4	2.2	1.0

Markers allele frequencies were determined by typing 100 normal ethnically matched samples, no. of alleles for marker D16S397 were 6 with frequencies (0.12, 0.20, 0.17, 0.11, 0.29 and 0.11), for marker D16S421, no. of alleles were 8 with frequencies (0.16, 0.21, 0.11, 0.17, 0.04, 0.14, 0.10, 0.07) and for marker D16S3086, no of alleles were found to be 7 with allele frequencies (0.13, 0.05, 0.26, 0.18, 0.09, 0.17, 0.12).