Table 1.
Biological process enriched with dysregulated genes induced by OVA/PM.a
| GO ID | Function name | Gene | q-Value |
|---|---|---|---|
| GO:0000074 | Regulation of progression through cell cycle | 13 | 3.22 × 10−3 |
| GO:0006260 | DNA replication | 12 | 3.84 × 10−5 |
| GO:0006355 | Regulation of transcription, DNA-dependent | 28 | 4.05 × 10−2 |
| GO:0006468 | Protein amino acid phosphorylation | 22 | 4.31 × 10−2 |
| GO:0006508 | Proteolysis | 26 | 6.59 × 10−4 |
| GO:0006811 | Ion transport | 21 | 1.94 × 10−2 |
| GO:0006817 | Phosphate transport | 6 | 8.36 × 10−3 |
| GO:0006911 | Phagocytosis, engulfment | 6 | 1.63 × 10−7 |
| GO:0006935 | Chemotaxis | 18 | 1.13 × 10−10 |
| GO:0006952 | Defense response | 12 | 3.60 × 10−4 |
| GO:0006954 | Inflammatory response | 34 | 1.56 × 10−10 |
| GO:0006955 | Immune response | 57 | 2.11 × 10−10 |
| GO:0006974 | Response to DNA damage stimulus | 10 | 2.37 × 10−2 |
| GO:0007049 | Cell cycle | 49 | 2.37 × 10−10 |
| GO:0007067 | Mitosis | 31 | 2.14 × 10−10 |
| GO:0007155 | Cell adhesion | 23 | 1.37 × 10−3 |
| GO:0007165 | Signal transduction | 41 | 2.59 × 10−4 |
| GO:0007166 | Cell surface receptor linked signal transduction | 9 | 8.33 × 10−4 |
| GO:0007242 | Intracellular signaling cascade | 17 | 2.56 × 10−2 |
| GO:0008283 | Cell proliferation | 7 | 3.13 × 10−2 |
| GO:0045087 | Innate immune response | 10 | 2.04 × 10−6 |
| GO:0051301 | Cell division | 40 | 2.16 × 10−10 |
a
GO categories identified by Onto-Express software; only biological processes with more than five genes and q-values < 0.05 are shown (see “Materials and Methods” for details).