Table 3.
Adjusted RRs for the association between 1999 U.S. EPA ASPEN modeled estimates of ambient benzene levels and lymphohematopoietic cancer incidence among children (< 20 years of age).
| Cancer type | Benzene level | No. of census tracts | No. of cases | Adjusted RRa (95% CI) | p-Value | p-Value for trend |
|---|---|---|---|---|---|---|
| Hodgkin’s disease | Low | 221 | 36 | 1.00 | ||
| Medium-low | 222 | 42 | 1.17 (0.74–1.85) | 0.500 | ||
| Medium-high | 221 | 31 | 1.07 (0.66–1.72) | 0.789 | ||
| High | 222 | 37 | 1.52 (0.92–2.52) | 0.101 | 0.163 | |
| NHL | Low | 221 | 42 | 1.00 | ||
| Medium-low | 222 | 40 | 0.96 (0.62–1.48) | 0.853 | ||
| Medium-high | 221 | 27 | 0.84 (0.52–1.36) | 0.484 | ||
| High | 222 | 28 | 1.06 (0.60–1.87) | 0.852 | 0.936 | |
| All leukemia | Low | 221 | 157 | 1.00 | ||
| Medium-low | 222 | 183 | 1.13 (0.91–1.40) | 0.269 | ||
| Medium-high | 221 | 156 | 1.10 (0.87–1.40) | 0.415 | ||
| High | 222 | 174 | 1.37 (1.05–1.78) | 0.019 | 0.034 | |
| ALL | Low | 221 | 116 | 1.00 | ||
| Medium-low | 222 | 147 | 1.23 (0.97–1.56) | 0.092 | ||
| Medium-high | 221 | 123 | 1.14 (0.87–1.49) | 0.349 | ||
| High | 222 | 124 | 1.24 (0.92–1.66) | 0.153 | 0.186 | |
| AML | Low | 221 | 21 | 1.00 | ||
| Medium-low | 222 | 20 | 0.93 (0.50–1.72) | 0.813 | ||
| Medium-high | 221 | 20 | 1.11 (0.59–2.10) | 0.747 | ||
| High | 222 | 31 | 2.02 (1.03–3.96) | 0.040 | 0.063 |
a
Adjusted for age, sex, race/ethnicity, and cSES.