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. 2008 Dec 1;105(49):19474–19479. doi: 10.1073/pnas.0810305105

Fig. 7.

Fig. 7.

L. acidophilus NCFM induces Th2 polarization via C-type DC-SIGN. DCs were maturated with L. acidophilus NCFM and the SlpA-knockout, NCK1377CI-(SlpB+) at a ratio of 100:1 (bacteria:DCs), or SlpA+LPS, in the presence or absence of anti-DC-SIGN Ab (aDC-SIGN). The percentage of IL-4- and INFγ-producing T cells was analyzed upon restimulation of the cultures. The data are the result of 4 independent experiments. *, significant difference (P < 0.05) for the cytokines induced after L. acidophilus NCFM stimulation.