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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2008 Aug 7;1778(11):2512–2519. doi: 10.1016/j.bbamem.2008.07.027

Fig. 2.

Fig. 2

Aβ42 caused vesicle membranes of rat brain lipid extract to become more molecularly-disordered. (A) The GP-GPo (GPo= −0.24±0.085, is the GP of control sample without treatment at time = 0) of Laurdan integrated in vesicle membranes of rat brain lipid extract after Aβ42 treatment exhibited only negative values, indicating more molecularly-disordered membranes. (B) The reversed amino acid sequence of Aβ, Aβ42-1, had no effect on the GP-GPo value. (*p < 0.02) (C) The GP distribution after treatments with Aβ1-42 and Aβ42-1; without treatment (upper); treatment with Aβ1-42 for 1 hr (middle); treatment with Aβ42-1 for 1 hr (lower).