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Aβ42 increased superoxide anion production through NADPH oxidase in DITNC cells. The fluorescent intensity of DHE was measured as an indicator of the superoxide anion (O2.−) production level in cells. (*p < 0.02) Apocynin suppressed the O2.− production induced by Aβ42, supporting that Aβ42 increases O2.− production in DITNC cells through NADPH oxidase.
