Fig. 5.

Effects of PLA₂ inhibitors on Aβ₄₂-induced membrane changes in the molecular order. The membrane biphasic order changes induced by Aβ₄₂ (1 µM) was totally suppressed by MAFP (5 µM) as indicated by GP-GP_o values (GP_o=0.074±0.06, is the GP of control cells pretreated with 5 µM of MAFP in DMSO) exhibiting negative numbers only (left), but was not suppressed by BEL (5 µM) (GP_o= −0.059±0.018, is the GP of control cells pretreated with 5 µM of BEL in DMSO) (right). (B) GP distribution after treatment with Aβ₄₂ for cells pretreated with MAFP (left) and BEL (right).