Figure 2.

Expression of differentiation and junctional markers in wt and null mutant adult epidermis. Cryosections (5 μm) of anterior foot pads from adult wt and galectin-7^−/− mice were stained. (A) Differentiation markers: keratin5 (K5) specific for basal cells, keratin10 (K10) specific for suprabasal cells and loricrin (Lor) specific for superficial granular layers. (B) Junctional markers E-cadherin (E-Cad), β-catenin (β-Cat), α6-integrin (α6), desmoglein (Dg), desmocollin1 (Dsc1), and plakoglobin (Pg). White lines indicate the dermoepidermal junction. Bar, 20 μm.