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. 2008 Dec;19(12):5478–5489. doi: 10.1091/mbc.E08-05-0448

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© 2008 by The American Society for Cell Biology

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Figure 7. — Patterning defects in the neural tube of zGRK2/3 morphant embryos. (A and B) Expression of nkx2.2 in injected embryos at 27 hpf in the neural tube (black arrow) between somites 5 and 10. (C–F) Expression of shh (C and D) and smo (E and F) in the trunk of injected embryos at 27 hpf. (G and H) Lateral views between somites 5 and 10 of 48-hpf injected islet1-GFP transgenic embryos. GFP labeling indicates significantly fewer motoneurons (white arrow) in the spinal cord and motor axon outgrowth defects of zGRK2/3 morphant embryos (white arrowhead). All pictures: anterior to the left, dorsal to the top.