Figure 6. Quantification of mRNA expression of retinal opsins, Thy1 and PACAP.

Short wavelength cone (SW), mid-wavelength cone (MW) opsins, rhodopsin and melanopsin mRNA expression are all significantly reduced in experimental glaucoma. The specific RGC marker Thy1 was also significantly reduced whereas PACAP expression is unchanged (t-test, * p<0.05; ** p<0.005.) Both of the retinas from each of the binocularly operated (n = 5) and control rats (n = 5) were used.