Table 1.
Summary statistics of the DEFB1 promoter region
| Population | |||||||
| AA | EA | YRI | AS | SAI | AUA | ||
| Na | 48 | 46 | 44 | 50 | 48 | 24 | |
| Sb | 22 | 16 | 23 | 17 | 16 | 17 | |
| θW (× 10-4) | DEFB1 | 35.41 | 26.00 | 37.71 | 27.11 | 25.75 | 32.52 |
| IIPGAc | 15.77 | 14.79 | NA | NA | NA | NA | |
| π (× 10-4) | DEFB1 | 53.73 | 53.28 | 45.85 | 54.96 | 23.037 | 51.84 |
| IIPGAc | 19.20 | 17.04 | NA | NA | NA | NA | |
| Tajima's D | DEFB1 | 1.68f | 3.29e | 0.71 | 3.21e | -0.33 | 2.13f |
| IIPGAc | 1.25 | 1.24 | NA | NA | NA | NA | |
| NIEHS (5 kb)d | 0.99 | 0.99 | 0.93 | >0.99 | NA | NA | |
| pg | 0.011 | 0.0001 | 0.092 | 0.0003 | NA | NA | |
| Fu and Li's D* | DEFB1 | 1.38f | 1.59f | 1.085 | 1.62e | 1.60f | 1.23 |
| IIPGAc | 1.35 | 1.36 | NA | NA | NA | NA | |
| NIEHS (5 kb)d | >0.99 | 0.98 | 0.97 | >0.99 | NA | NA | |
| pg | 0.0058 | 0.0001 | 0.069 | <0.0001 | NA | NA | |
| Fu and Li's F* | DEFB1 | 1.76f | 2.56e | 1.13 | 2.56e | 1.12 | 1.76f |
| IIPGAc | 1.46 | 1.14 | NA | NA | NA | NA | |
| NIEHS (5 kb)d | >0.99 | 0.99 | 0.96 | >0.99 | NA | NA | |
| pg | 0.0031 | <0.0001 | 0.045 | <0.0001 | NA | NA | |
aSample size. bNumber of segregating sites. cMaximum values for 20 IIPGA gene promoters. dPercentile rank relative to the distribution of 5 kb regions deriving from NIEHS genes. ep-value (standard neutral model) <0.01. fp-value (standard neutral model) <0.05. gp-values obtained by applying a calibrated population genetics model, as described in the text. NA, not available.