Table 5.

Clusters of genes deregulated in trx mutants conserved in other phylogenetically related species

		Genes (orthologs)
Species	Genome	↑	↓	Clusters ↑	Clusters ↓	Clusters	Deregulated genes in clusters
D. melanogaster	19,670	260	275	10	15	25	97
D. simulans	17,927	235	262	7	13	20	75
D. yakuba	19,929	259	275	11	14	25	96
D. pseudoobscura	15,096	170	230	1	13	14	60
A. gambiae	7,283	97	151	2	5	7	34

For each species, we show: number of genes for which an ortholog in D. melanogaster was found, number of orthologs for up-regulated genes, number of orthologs for down-regulated genes, number of up-regulated clusters, number of down-regulated clusters, total number of clusters, number of deregulated genes from D. melanogaster that constitute the clusters.