Table 4.
Early and late acute kidney injury: characteristics, multiple organ failure, and sepsis
Early AKI (n = 17) | Late AKI (n = 14) | P value | |
Age, years | 48.9 (39.7 to 58.1) | 62.6 (49.7 to 75.5) | 0.07 |
Total body surface area, percentage burned | 53.3 (41.0 to 65.6) | 39.8 (26.4 to 53.2) | 0.13 |
Full thickness burns, percentage | 39.4 (28.1 to 50.7) | 23.0 (12.2 to 33.8) | 0.04 |
Multiple organ failure | 14 | 10 | 0.47 |
Sepsis | 15 | 12 | 0.83 |
Lowest value of MAP for days 1–3, mm Hg | 57.5 (54.9 to 60.2) | 59.1 (54.3 to 63.9) | 0.53 |
Plasma myoglobin for days 1–2, μg/L | 1,167 (-484 to 2,820) | 220 (103 to 337) | 0.24 |
Mechanical ventilation | 17 | 13 | - |
Length of stay, days | 45.7 (27.8 to 63.6) | 60.6 (27.9 to 93.4) | 0.37 |
Data are mean (95% confidence interval) or number of patients. Early acute kidney injury (AKI) is defined as when creatinine reached the level for Risk within the first 7 days; late AKI occurred between days 8 and 60. Multiple organ failure is defined as 3 to 4 score points in two or more organ dimensions of the sequential organ failure assessment score. (Contingency table, Pearson chi-square test for categorical variables, and Student t test for continuous data.) MAP, mean arterial pressure.