Table 3.

Association of C/T polymorphism of the GDF5 gene with CDH when stratified by gender

Groups compared	TT vs. other combined			CC vs. other combined			T allele vs. C allele			All genotype
	OR	P value	95% CI	OR	P value	95% CI	OR	P value	95% CI	P value
All patients (n = 338) vs all controls (n = 622)	1.41	0.013	1.08 to 1.85	0.50	0.029	0.27 to 0.94	1.40	0.0037	1.11 to 1.75	0.014
Female patients (n = 291) vs female controls (n = 316)	1.52	0.012	1.10 to 2.10	0.50	0.061	0.24 to 1.05	1.46	0.0053	1.21 to 1.91	0.020
Male patients (n = 47) vs male controls (n = 306)	1.24	0.51	0.66 to 2.33	0.55	0.42	0.12 to 2.40	1.27	0.38	0.75 to 2.14	0.65

CDH = congenital dysplasia of the hip; CI = confidence interval; GDF5 = growth differentiate factor 5; OR = odds ratio.