Table 4.

Association of C/T polymorphism of the GDF5 gene with CDH when stratified by severity

Groups compared	TT vs. other combined			CC vs. other combined			T allele vs. C allele			All genotype
	OR	P value	95% CI	OR	P value	95% CI	OR	P value	95% CI	P value
Patients with hip dislocation (n = 264) vs all controls (n = 622)	1.41	0.023	1.05 to 1.89	0.49	0.044	0.24 to 0.99	1.40	0.0078	1.09 to 1.79	0.028
Patients with hip subluxation (n = 53) vs all controls (n = 622)	1.35	0.31	0.76 to 2.41	0.49	0.32	0.12 to 2.08	1.36	0.22	0.83 to 2.20	0.46
Patients with hip instability (n = 21) vs all controls (n = 622)	1.64	0.29	0.65 to 4.11	0.63	0.65	0.08 to 4.77	1.51	0.30	0.69 to 3.29	0.57

CDH = congenital dysplasia of the hip; CI = confidence interval; GDF5 = growth differentiate factor 5; OR = odds ratio.