Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Dec 1;183(5):909–921. doi: 10.1083/jcb.200808034

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — CAPs in optic nerve from Claudin 11–null mice. (A and B) Representative CAP series from optic nerves of wild-type (+/+) and Claudin 11–null (−/−) mice showing three components (arrows) elicited by square voltage pulses with varied amplitudes. (B) Arrowhead, hyperpolarizing afterpotential from −/− nerves. (C) CVs (top) and amplitudes (bottom) were measured at peak maxima (mean ± SD) from n = 8 (+/+) and n = 7 (−/−) optic nerves. (D–F) Axon recruitment profiles for each component. Greater voltages are required to recruit the majority of fibers from Claudin 11–null mice (open symbols) compared with controls (closed symbols). Error bars indicate SD.