TABLE 1.

Biophysical properties of the analogous OAKs

OAK	Ha	Value at a Q of 3 forb:								RBC LC50c
		E. coli		P. aeruginosa		E. faecalis		S. aureus
		MIC	MBC	MIC	MBC	MIC	MBC	MIC	MBC
c16KKc12K	62	25-50	>50	25->50	>50	6-25	25->50	3-6	25->50	15 ± 1.5
c16(ω7)KKc12K	57	6	12.5	12.5	50	6	6	3	6	8.5 ± 1

^aH, hydrophobicity measure as determined by HPLC. The H values represent percentages of the acetonitrile eluent in a C₁₈ column.

^bQ, molecular charge under physiological conditions. MIC, MIC (μM) that induced a 100% inhibition of proliferation after overnight incubation at 37°C.

^cRBC LC₅₀, OAK concentration (μM) that induced 50% hemolysis of a 1% RBC dilution, after 3 h of incubation in PBS at 37°C. Values were rounded up to the nearest half unit and represent the means ± standard deviations obtained from at least four independent experiments performed in duplicate. The lack of a range indicates consistency.