TABLE 2.
OAKs' binding properties to a model phospholipid membranea
| OAK | Concn rangeb | Kadhesion (M−1) | Kinsertion | Kapparent (M−1) |
|---|---|---|---|---|
| c16KKc12K | Low | 2.2 × 106 | 10.3 | 8.3 × 107 |
| High | 4.3 × 105 | 0.1 | 4.3 × 104 | |
| c16(ω7)KKc12K | Low | 2.1 × 106 | 8.1 | 1.7 × 107 |
| High | 1.5 × 106 | 10.1 | 4.5 × 107 |
a
SPR affinity constants were calculated from an average of five duplicated binding curves for each OAK.
b
Low concentrations were 0.16, 0.31, 0.62, 1.25, and 2.5 μM. High concentrations were 3.1, 6.25, 12.5, 25, and 50 μM. χ2 (reflecting the best fit) ranged between 2.5 and 10.