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Cumulative mortality of mice infected with a flucytosine-resistant A. fumigatus isolate (isolate AZN 58) (A) compared with that of mice infected with a flucytosine-susceptible isolate (AZN 8196) (B) (9) in groups treated with flucytosine and control groups. Groups of 10 mice each were treated with flucytosine for 7 days starting 2 h after inoculation. ▪, 200 mg/kg q6h; □, 200 mg/kg q12h; ▴, 100 mg/kg q6h; Δ, 100 mg/kg q12h; •, controls.
