Table 1.
Inhibitors | % inhibitiona | Structure |
---|---|---|
Biotinyl anilide | 55±0.1 | |
Biotinyl allylamide | 37±0.09 | |
Biotinyl N-methylanilide | 26±0.05 | |
Biotinyl methyl 4-(amidomethyl) benzoate | 80±0.02 | |
Biotinyl 2-amido-pyridine | 40±0.05 | |
Biotinyl 4-amidophenylboronic acid | 53±0.02 | |
Biotinyl benzylamide | 47±0.01 |
Percent inhibition compared with inhibitor-free control after 2 hours of incubation of BTD + inhibitor + substrate. Values are means ± SD (n = 6; P < 0.05 compared with inhibitor-free control).