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. Author manuscript; available in PMC: 2009 Dec 20.
Published in final edited form as: J Comp Neurol. 2008 Dec 20;511(6):832–846. doi: 10.1002/cne.21866

Figure 2.

Figure 2

Electron micrographs of AMPAR GluR1 subunit immunogold labeling in hippocampal CA1 SR from control and FZP-withdrawn rats. (A-C) Representative images of GluR1-labeled (Chemicon) asymmetric synapses from control rats. Immunogold particles (10 nm) are located primarily within the postsynaptic density (PSD) and extend into the synaptic cleft. (D-F) Representative images of GluR1-labeled asymmetric synapses from FZP-withdrawn rats also show immunogold labeling within the PSD and synaptic cleft. GluR1 immunogold labeling was significantly increased in FZP-withdrawn CA1 synapses compared to controls (see Table 1 and Fig. 3). Scale bar in F is 0.25 μm. All images are at the same magnification.