TABLE 4.

Genes whose average mRNA ratios were altered by a factor of three or more^a in acetate minimal medium for C. glutamicum WT compared with the ΔsugR mutant

Gene IDb	Gene name, gene product, and/or deduced function	mRNA ratio (ΔsugR mutant/WT)c
cg2925	ptsS, sucrose-specific enzyme II of the PTS	50.7
cg2119	pfkB, 1-phosphofructokinase protein	47.8
cg2120	ptsF, fructose-specific enzyme II of the PTS	32.3
cg2118	fruK, DeoR-type transcriptional regulator	26.9
cg2117	ptsI, enzyme I of the PTS	11.1
cg2121	ptsH, phosphocarrier protein HPr	9.0
cg3219	ldhA, NAD-dependent l-lactate dehydrogenase	6.7
cg0812	dtsR1, acetyl/propionyl-CoA carboxylase beta chain	6.6
cg0957	fas-IB, fatty acid synthase	5.9
cg2116	Putative phosphofructokinase	5.4
cg1290	metE, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase	4.8
cg3218	pyk, pyruvate kinase	4.3
cg1763	sufD, components of an uncharacterized iron-regulated ABC-type transporter	3.6
cg1112	Septum formation initiator, secreted protein	3.6
cg0791	pyc, pyruvate carboxylase	3.5
cg0634	rplO, 50S ribosomal protein L15	3.5
cg2430	Hypothetical protein	3.5
cg1111	eno, enolase	3.3
cg3227	lldD, quinone-dependent l-lactate dehydrogenase	3.1
cg2419	pepB, leucyl aminopeptidase	3.1
cg1379	ssuB, aliphatic sulfonates ATP-binding ABC transporter protein	3.1
cg0604	rpsQ, 30S ribosomal protein S17	3.0
cg1977	Putative secreted protein	3.0
cg1537	ptsG, glucose-specific enzyme II of the PTS	3.0
cg1673	ppmN, polyprenol-phosphate-mannose synthase	0.3
cg2425	Predicted permease	0.3
cg3368	ABC transporter permease protein	0.2
cg2071	int2′, putative phage integrase (N-terminal fragment)	0.2
cg2115	sugR, transcriptional regulator of sugar metabolism	0.1

^aP < 0.05.

^bGene numbering, gene designations, and descriptions of gene products are for NC006958.

^cThe mRNA ratios represent average values obtained from three DNA microarray experiments performed with RNA isolated from three independent cultures in acetate minimal medium.