TABLE 2.
Performance of alternative rapid HIV antibody test algorithms in field investigation
| Testing algorithm | HIV infecteda
|
HIV uninfected
|
Sensitivity (%) | Specificity (%) | PV+ (%)b | PV− (%)b | ||
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |||||
| Capillus alone | 1,946 | 6 | 25 | 10,746 | 99.7 | 99.8 | 98.7 | 99.9 |
| Determine alone | 1,944 | 8 | 10 | 10,761 | 99.6 | 99.9 | 99.5 | 99.9 |
| Sequential (initial Capillus)c | 1,946 | 6 | 0 | 10,771 | 99.7 | 100.0 | 100.0 | 99.9 |
| Sequential (initial Determine)d | 1,944 | 8 | 0 | 10,771 | 99.6 | 100.0 | 100.0 | 99.9 |
a
Based on two rapid HIV antibody tests (if concordant) or ELISA (if two rapid HIV antibody tests are discordant).
b
Predictive values are calculated for this study population with 15.1% HIV seroprevalence and would vary in populations with different prevalence.
c
As shown in Fig. 2a.
d
As shown in Fig. 2b.