TABLE 3.
Reactivities of the eight swine NoV-specific MAbs
| MAb namea | Reactivity
|
|||||
|---|---|---|---|---|---|---|
| SwVA34 VLPsb | SwVA34 VLPsc | GII.4 VLPsd | N/S domaine | P domaine | P2 domaine | |
| SwNV3A10 | + | + | + | + | − | − |
| SwNV6E11 | + | + | + | + | − | − |
| SwNV2C1 | + | − | − | − | − | − |
| SwNV6C9 | + | − | − | − | − | − |
| SwNV8C12 | + | − | − | − | − | − |
| SwNV8E12 | + | − | − | − | − | − |
| SwNV8F10 | + | − | − | − | − | − |
| SwNV8B10 | + | − | − | − | − | − |
a
All MAbs were of the IgG1 isotype.
b
Recognition of the swine NoV VLPs of strain SwVA34 by ELISA.
c
Recognition of the swine NoV VLPs of strain SwVA34 by Western blotting.
d
Recognition of the human NoV VLPs of GII.4 (strain Ast6139/01/Sp) by ELISA.
e
Recognition of the N/S, P, or P2 domain of the SwVA34 capsid protein by ELISA.