FIG. 1.

Mapping of CD8 T-cell epitopes in the MHV-68 genome. Sequences of the identified epitopes are mapped to their respective positions in the MHV-68 genome. The upper row depicts ORFs labeled as essential (blue) or nonessential (gray) genes, with the identity of the respective ORF from which the epitopes derive shown (22). In the lower row, the arrows indicate the transcriptional profile of the respective ORFs (1, 7, 18). Early-Late (E-L) refers to transcriptional classes in which both E and L gene expression has been demonstrated (1, 18). Sequences for previously identified epitopes are denoted with an asterisk, and H-2D^b epitopes are shaded in gray.