FIG. 2.

Mechanism of 3Dpol-RNA primer-template complex assembly and nucleotide incorporation. A minimal kinetic mechanism for single-nucleotide addition by PV 3Dpol is shown. X, inactivated 3Dpol.

Mechanism of 3Dpol-RNA primer-template complex assembly and nucleotide incorporation. A minimal kinetic mechanism for single-nucleotide addition by PV 3Dpol is shown. X, inactivated 3Dpol.