FIG. 2.
Mortality data for SCID/ICR mice inoculated with YF5.2iv, 305V, 326E, 380T, or SPYF-H3 virus. Mice were inoculated with 5 × 105 PFU by the i.p. route and observed as described in Materials and Methods. Shown are mortality percentages for groups of 10 mice, except for 326E (12 mice) and SPYF-H3 (13 mice). The P values (two sided) for comparisons among groups based on mortality at 50 days were as follows: SPYF-H3 versus 326E, P = 0.67; SPYF-H3 versus 5.2 or 380T, P = 0.0054; SPYF-H3 versus 305V, P = 0.0007; YF5.2iv versus 326E, P = 0.0019; YF5.2iv or 380T versus 305V, P = 0.999; 326E versus 305V, P = 0.0001. The average survival time data in days (mean ± standard deviation, median) were as follows: SPYF-H3, 22.9 ± 11.2, 18; 326E, 18 ± 9.7, 15. The P value (two sided) for comparison of average survival times (log rank test) was 0.23.