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. 2008 Oct 8;82(24):12069–12081. doi: 10.1128/JVI.01379-08

TABLE 2.

VHH kinetic constants and affinities for IIIB gp120a

VHH KD (nM) ka [1/(M·s)] kD (1/s)
A12 0.1 2.73 × 105 2.98 × 10−5
D7 0.097 4.00 × 105 3.89 × 10−5
C8 0.85 2.05 × 105 1.74 × 10−4
a

VHH A12, D7, and C8 association rate constants (ka), dissociation rate constants (kD), and equilibrium dissociation constants (KD = kD/ka) for recombinant IIIB gp120 were determined in surface plasmon resonance studies.