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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Drug Metab Dispos. 2008 Aug 21;36(11):2244–2251. doi: 10.1124/dmd.108.022996

Fig. 3.

Fig. 3

Effect of treatment with GHB alone or GHB with L-lactate, GHB with D-mannitol, or GHB with the combination of D-mannitol/L-lactate on urine pH and volume. Urine pH changes (A) and urine volume changes (B) after administration of 60.5 mg h−1 kg−1 L-lactate, 0.5 g/kg D-mannitol, and the combination of D-mannitol and L-lactate. One-way ANOVA followed by Dunnett's test, n = 3 to 5, mean ± S.D. *, p < 0.05; **, p < 0.01.