. Author manuscript; available in PMC: 2009 Oct 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2008 Jul 1;232(1):78–85. doi: 10.1016/j.taap.2008.06.007

Table 1.

Activities of antioxidant enzymes in 240 day old female ACI rats

Tissue	SOD (U/mg protein)	CAT (nmol/min/mg protein)	GPx (nmol/min/mg protein)
Female ACI rats were treated with an E₂ pellet (s.c., 3 mg E₂ + 17 mg cholesterol) for 240 days. Control rats were implanted with a pellet containing 17 mg cholesterol only. The activities of the antioxidant enzymes SOD, GPx and CAT were measured in mammary and liver tissue from control and E₂-treated rats from the 240 day treatment group. Enzyme activity was assessed in mammary tumor tissue as well. The data are reported as an average of values obtained for at least 7 different animals ± SE.
Control Mammary	561 ± 70	88 ± 9	92 ± 9
E2-Treated Mammary	1747 ± 460^*	104 ± 12	128 ± 22
Mammary Tumor	1031 ± 211^*	65 ± 5	232 ± 37^*
Control Liver	169 ± 11	1290 ± 170	601 ± 88
E2-Treated Liver	152 ± 13	1270 ± 350	1170 ± 81^*

Indicates a p value <0.05 compared to control mammary or liver compared to respective age-matched controls.