Fig. 6.

A: body weight of C57BL/6J mice maintained on low-calorie diet (▪) or high-calorie (60 kcal fat) diet with (○) or without (•) supplementation of l-arginine. B: leptin concentration changes in blood plasma of C57BL/6J mice maintained on low-calorie diet (▪) or high-calorie D-12492 (60 kcal fat) diet with (○) or without supplementation (•) of l-arginine (•). *P < 0.05 vs. control mice (low-calorie diet); n = 4 to 5 mice. C: leptin vs. body weight linear plot (r = 0.93, P < 0.05) for the low-calorie diet (▪, solid line) or exponential plot (r² = 0.95, P < 0.0001) for high-calorie diet D-12492 (60 kcal fat) diet (○, dashed line).