Fig. 7.

A: eNOS expression in aortic endothelial cells of C57BL/6J mice maintained on a low-calorie diet (control, white bars) and high-calorie diet (60 kcal fat; black bars) for 105 Days. B: cGMP content in aortic wall of C57BL/6J mice maintained on a low-calorie diet (control, black bars) and a high-calorie diet (60 kcal fat; white bars) *P < 0.005, n = 4 to 5 mice. C: CaI (1 μmol/l)-stimulated NO, O₂⁻, and ONOO⁻ release from aortic endothelial cells of C57BL/6J mice maintained for 105 days on low-calorie diet (black bars) or high-calorie (60 kcal fat, white bars) with or without supplementation with l-arginine (100 mg·kg⁻¹·day⁻¹) or l-arginine (100 mg·kg⁻¹·day⁻¹) and sepiapterin (10 mg·kg⁻¹·day⁻¹). *P < 0.01 vs. control (low-calorie diet); #P < 0.05 vs. obese mice without l-arginine supplementation; n = 4 to 5 mice.