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Hemodynamic responses to a brief (10 min) DA compression alone, after l-NA administration, and with and without fasudil treatment, expressed as the percent change in PVR from baseline (n = 6). Compared with DA compression alone, DA compression after l-NA injection increased PVR. Fasudil treatment completely blocked the increase in PVR (P < 0.05 for all comparisons). Values are means ± SE. *P < 0.05; ***P < 0.001.
