Table 1.

SR proteins in WT, I-2¹⁴⁰, PP1, and DT mouse hearts

	WT	I-2140	PP1	DT
PLB	100±1.8	103±4.9	93.0±5.7	108±4.4
SERCA2a	100±4.8	121±5.0*	83.6±5.7*	92.6±9.5
Ryanodine receptor	100±7.1	133±1.7*	68.7±4.7*	75.5±3*

Data are expressed as means ± SE % of wild-type (WT) value; n = 9–12 hearts. Expression of cardiac regulatory sarcoplasmic reticulum (SR) proteins in homogenates of WT, protein phosphatase 1-overexpressing (PP1), COOH-terminally truncated PP1 inhibitor-2-overexpressing (I-2¹⁴⁰), and double transgenic (DT) mouse hearts was determined by Western blotting. PLB, phospholamban; SERCA2a, sarco(endo)plasmic reticulum Ca²⁺-ATPase 2a.

^*P < 0.05 vs. WT.