Table 2.

Morphometric parameters of WT and transgenic mice

	n	Body Weight, g	Heart Weight, mg	Heart-to-Body Weight Ratio, mg/g
30 wk of age
WT	20	31.9±0.7	190±7.9	6.0±0.2
I-2140	16	28.7±1.1	167±8.6	5.9±0.3
PP1	20	29.3±0.9	255±31.0*	9.1±1.4*
DT	21	28.8±1.0	166±8.1	5.8±0.3
12 wk of age
WT	7	24±1.4	144±7.7	5.9±0.2
I-2140	6	27.2±1.2	143±6.6	5.3±0.1
PP1	6	25.8±1.0	143±8.4	5.5±0.1
DT	6	27.4±0.9	152±7.2	5.6±0.5
12 wk of age
WT	12	26±1.2	139±6.9	5.4±0.1
I-2140	8	28.4±1.3	144±5.6	5.1±0.2
PP2A	7	26.9±1.4	200±19.1*	7.7±0.4*
PP2A-I-2140	12	28.5±1.1	192±8.3*	6.8±0.3*

Values are means ± SE for n hearts. Body weight and heart weight were determined in WT, I-2¹⁴⁰, PP1, DT, PP2A, and PP2A-I-2¹⁴⁰ double transgenic mice.

^*P < 0.05 vs. WT.