Table 2.
Average diameter and the consequent FMD response before and during cuff inflation
| Shear Rate AUC, 104 | Dpreinfl | Dinfl | P Value | FMD Dpreinfl | FMD Dinfl | P Value | |
|---|---|---|---|---|---|---|---|
| Total | 2.7±1.7 | 3.46±1.0 | 3.51±1.0 | <0.001 | 8.9±4.7 | 7.1±4.9 | <0.001 |
| Children | 3.6±1.8* | 2.63±0.5 | 2.67±0.5 | 0.02 | 11.2±5.1 | 9.4±5.2 | 0.02 |
| Adults | 1.7±1.0 | 4.17±0.5 | 4.27±0.5 | <0.001 | 7.3±3.2 | 4.6±3.3 | <0.001 |
| Older subjects | 2.1±1.1 | 4.13±0.8 | 4.15±0.9 | 0.59 | 6.3±3.4 | 6.0±4.2 | 0.77 |
Data are means ± SD; n, no. of participants/group. Average diameter before inflation (Dpreinfl) and during cuff inflation (Dinfl) and the consequent flow-mediated dilation (FMD) response using the baseline diameter before FMD Dpreinfl or during FMD Dinfl presented for all subjects (n = 98) and in three groups: children (n = 45), adults (n = 31), and older subjects (n = 22). Shear rate area under the curve (AUC) peak diameter is presented as being the most appropriate eliciting stimulus for the FMD response (Ref. 29) for all subjects (n = 91), children (n = 44), adults (n = 25), and older subjects (n = 22). P values represent a paired t-test.
Significantly different from young and older adults (unpaired t-test).