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Under homeostatic conditions, senescent neutrophils are cleared in equal proportions by the spleen, liver, and bone marrow. Purified, senescent neutrophils labeled with 111In were administered i.v. into recipient mice. Organs were harvested after 2 h, and the radioactivity in each tissue was calculated as a percentage of the total present in the whole animal. Data are presented as mean ± se; n = 7 experiments, 3 mice/group.
