TABLE 1.
IFN type | IFN class(es) | Receptor | Pathway |
---|---|---|---|
I | α, β, δ, ω | IFN-α/β (IFNAR1, IFNAR2) | ISGF3 (STAT1/STAT2/IRF9) |
I | τ (also known as ε) | IFN-α/β (IFNAR1, IFNAR2) | Pregnancy specific |
II | γ | IFN-γ (IFNGR1, IFNGR2) | STAT1/STAT1 homodimers |
III | λ | 1L-28α/IL-1ORβ | ISGF3 |