. 2008 Dec;72(4):590–641. doi: 10.1128/MMBR.00016-08

TABLE 7.

Steroidal estradiols and estrogen metabolites

Name	Molecular formula	Source	Other names	Inhibitory potency, I₅₀ (reference)
4-Hydroxyestradiol	C₁₈H₂₄O₃	Natural estrogen	4-Hydroxyestradiol-17β; 4-hydroxy-17-β−estradiol; estra-1,3,5(10)-triene-3,4,17-β-triol	55 μM (rat brain MF₀F₁-ATPase) (451)
2-Hydroxyestradiol	C₁₈H₂₄O₃	Natural estrogen	(17β)-Estra-1,3,5(10)-triene-2,3,17-triol; estra-1,3,5(10)-triene-2,3,17-β-triol	110 μM (rat brain MF₀F₁-ATPase) (451)
17-α-Estradiol	C₁₈H₂₄O₂	Natural estrogen	1,3,5-Estratriene-3,17-α-diol; 3,17-dihydroxyestratriene; 3,17-α-dihydroxyoestra-1,3,5(10)-triene; epiestradial; epiestradiol; estra-1,3,5(10)-triene-3,17α-diol; oestra-1,3,5(10)-triene-3,17α-diol; estradiol-17-α; α-estradiol	25% inhibition at 42 μM (rat brain MF₀F₁-ATPase) (451)
17-β-Estradiol	C₁₈H₂₄O₂	Natural estrogen	1,3,5-Estratriene-3,17-β-diol; 17-β-estra-1,3,5(10)-triene-3,17-diol; 17-β-OH-estradiol; 17-β-OH-estradiol; 17-β-oestra-1,3,5(10)-triene-3,17-diol; 17β-oestra-1,3,5(10)-triene-3,17-diol; 3,17-epidihydroxyestratriene; 3,17-epidihydroxyoestratriene; 3,17-β-dihydroxy-1,3,5(10)-oestratriene; 3,17-β-estradiol; 3,17-β−estradiol; Aerodiol; Aquadiol	7% inhibition at 14 μM (rat brain MF₀F₁-ATPase) (451)
α-Zearalenol	C₁₈H₂₄O₅	Natural mycoestrogen	(4S,8R,12E)-8,16,18-Trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-12,15,17,19-tetraen-2-one; trans-zearalenol	50 μM (rat brain MF₀F₁-ATPase) (451)
β-Zearalanol	C₁₈H₂₄O₅	Natural mycoestrogen	(8S,12E)-8,16,18-Trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-12,15,17,19-tetraen-2-one	150-200 μM (rat brain MF₀F₁-ATPase) (451)