Table 1.

Genotype and allele frequencies of coding-nucleotide-polymorphisms (cSNPs) in human PRDM9 in patient and control groups

Sequence change	Classification of change	Alteration in amino acid sequence	Frequency of SNP in patients		Frequency of SNP in controls		Fisher’s exact test
			Allele (%)	Genotype (%)	Allele (%)	Genotype (%)	AlleleP	GenotypeP
Exon2 C(224)T	SNP1	Silent	1/35 (2.86%)	T/C1/17(5.88%)	9/691 (1.3%)	T/C9/341 (2.6%)	0.396	0.398
Exon6 C(614)T	SNP2	Silent	1/35 (2.86%)	T/C1/17(5.88%)	0/700 (0.0%)	T/C 0/350 (0.0%)	0.049a	0.049a
Exon9T(1086)C	SNP3	Missense Tyr→His	2/34 (5.88%)	C/T 2/16(12.5%)	1/699 (0.14%)	C/T1/349 (0.29%)	0.0069a	0.0066a

^aStatistically significant