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EM of Aβ40 fibrils with and without peptide inhibitors I1 and I10. Images were obtained at three different magnifications: 4,800× (A, B, C), 49,000× (D,E,F) and 98,000× (G,H,I). The images were obtained after 72 h of incubation at 37°C. The concentration of Aβ40 was 40 μM for all experiments, and the molar ratio of Aβ40-to-inhibitor was 1:1.
