Table 1.

Inhibition constants (Ki, nM) of compounds on I-125-IMPY binding to amyloid plaques in AD brain homogenates

Compound	Ki ± SEM (nM)	Compound	Ki ± SEM (nM)
2a	95 ± 8.0	3e	15 ± 6
2e	15 ± 4.0	3j	80 ± 20
3a	1.1 ± 0.2	4a (SB-13)	1.2 ± 0.2*
3b	59 ± 10	4c	32.5 ± 5.0
3c	38 ± 5	4e	5.0 ± 1.2
3d	150 ± 30	PIB	2.8 ± 0.5

Each value was determined three times with duplicate for each measurement.

^*The value was reported previously ¹⁹ .