Figure 5.
Overlay of SA2-13 and HEPES when bound to SHV-1. The active sites of the HEPES bound SHV-2 structure and that of our SA2-13 wt SHV-1 structure were superimposed. The figure shows the active site of wt SHV-1 depicting both SA2-13 (blue stick) and HEPES (yellow stick) illustrating the similar position of the sulfone+linker moiety of HEPES and that of the carboxyl+linker moiety of SA2-13.