Skip to main content
. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Surgery. 2008 Jul 25;144(3):353–366. doi: 10.1016/j.surg.2008.05.007

Figure 1. Signaling specificity of Smad proteins as they relate to TGF-β ligands, Ligand Binding Traps and the Type I and Type II receptors.

Figure 1

Important ligand traps, ligands, and receptor complexes in TGF-β superfamily signaling are noted. Downstream R-Smads 1, 2, 3, 5 and 8 are grouped based on their signaling specificity. Adapted from9.