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. Author manuscript; available in PMC: 2008 Dec 4.
Published in final edited form as: Chem Res Toxicol. 2006 Oct;19(10):1386–1392. doi: 10.1021/tx060154d

Table 1.

Precision of the LC-ESI-MS/MS method for Cro-dGuo in DNA

Cro-dGuo levels (fmol/μmol dGuo)a
(CV, %) (n=6)
Interday variation
CV, %
Day 1 Day 2
Samples (6S, 8S) (6R, 8R) (6S, 8S) (6R, 8R) (6S, 8S) (6R, 8R)
Calf thymus DNA 1 18.8 ± 2.2 (12%) 16.6 ± 1.9 (11%) 19.7 ± 3.6 (18%) 17.7 ± 3.2 (18%) 3.3 4.5
Calf thymus DNA 2 4.58 ± 0.67 (15%) 5.22 ± 0.22 (4.2%) 4.91 ± 0.32 (6.5%) 5.45 ± 0.33 (6.1%) 5.4 3.0
a

0.8 – 1.2 mg of DNA was used for each analysis.