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. 2008 Nov 18;105(48):18806–18811. doi: 10.1073/pnas.0807345105

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© 2008 by The National Academy of Sciences of the USA

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Fig. 4. — Gene expression analysis of the pharyngeal arches in Ednra^Edn1^/+ embryos. (A–T) Whole-mount in situ hybridization for Dlx2 (A and B), Fgf8 (C and D), Dlx5 (E and F), Dlx6 (G and H), Dlx3 (I and J), Pitx1 (K and L), Goosecoid (M–P), and Hand2 (Q–T) in E10.5 wild-type (A, C, E, G, I, K, M, O, Q, and S) and Ednra^Edn1^/+ (B, D, F, H, J, L, N, P, R, and T) embryos. Arrows indicate the junction of maxillary and mandibular arches. Yellow arrowheads indicate ectopic gene expression in the maxillary arch. hy, hyoid arch; md, mandibular arch; mx, maxillary arch.